Luke Waterfall and Josh Ginnelly will be assessed ahead of Lincoln's first home game back in the Football League against Morecambe.
Captain Waterfall has missed the first two games of the season with a knee injury while winger Ginnelly sat out the Carabao Cup tie at Rotherham after suffering an ankle knock at Wycombe last weekend.
Josh Vickers, Billy Knott, Harry Anderson and Jordan Maguire-Drew were the four changes made by Danny Cowley in the cup and the Imps boss has said their performances have given him food for thought when it comes to his team selection on Saturday.
Sam Habergham is back in training and is scheduled to play in a reserve game next week in the hope that the left-back, who had two hernia operations over the summer, will then be back in first team contention.
Elliot Osborne could make his Morecambe debut following his arrival this week.
The 21-year-old Fleetwood midfielder joined the Shrimps on Wednesday on loan until January.
Defender Mitchell Lund, who came off early in the second half of Tuesday's Carabao Cup loss to Barnsley, has a groin problem and may miss out.
Having made five changes to his starting line-up for that game, boss Jim Bentley is expected to recall players for the fixture at Sincil Bank.